The excessive relationship of the fexofenadine medicine is unusual and therefore, it interests is not asserted. The dead women have not introduced themselves in the test in the mouse, in 5.000 mg/kg, are 110 times the more remarkablly dose that suggests for the person of the adult. Ulterior studies have not demonstrated the dead women in the mouse from the similar centralism, cares with 400 times the dose that suggests in the person of the adult. To capacity of search of the person from only the 800 doses of milligrammi, in the first place to a month of the two 690 doses of milligrammo, meaningful clinician does not have the contrary effect, when he compares to the placebo. Causes? the part, two fenile group was uses in the first place introduced Grignard to answer in the foreign, for terziario etilico alcohol. The group of the amine then from the alchilazione with the aldehyde that protegge, therefore the aldehyde res-establish from the deprotection with acid. The molecular causes surplus of the part from the double alchilazione from the iodomethane of carbanion taking place itself from the nitrile. Group of the nitrile then from the hydrolisis to idrossilato acid. The aromatic bromide of the idrossile is then lithiated the residual one of the organolitio of production, is possibly unified gives the more subsequently (in workup from the part of the aldehyde) fexofenadine.
